Carbetocin versus Oxytocin in placental separation and postpartum haemorrhage in caesarean section-comparative observational study

Background: Carbetocin and oxytocin are indicated for the prevention of postpartum haemorrhage (PPH) due to uterine atony. is a newer analogue with longer half life more heat stable. PPH can be effectively reduced by prophylactic use uterotonics. The aims present study were compare effects carbetocin in separation placenta, controlling blood loss additional uterotonic needed caesarean section (CS) at high risk primary PPH. Methods: Women group (group A) received bolus 100 µg IV; women control B) 20 IU 1000 ml 0.9% NaCl solution IV (150 mL/ hour). efficacy drugs was evaluated. Also, haemodynamic need agents compared. In addition, we compared drop haemoglobin level, placental separation, tone. Results: Both produce hypotension but effect greater group. Placental seen early Uterine tone attained earlier however maintained persistently Additional (46% vs 0%, p=0.05). Conclusions: A single injection appears effective than continuous infusion maintain sustained adequate prevent However, there delayed attainment after carbetocin.